New immunosuppressive agents in pediatric transplantation
نویسندگان
چکیده
منابع مشابه
State of immunosuppressive agents in organ transplantation.
TRANSPLANT A nON has been built on the foundation of using drug thera.py to nonspecifically suppress the recipient immune response. Failure to achieve adequate immunosuppression is associated with a high incidence of graft loss from rejection. The present goal of immunosuppressive regimens is to suppress the immune response to the allograft while preserving sufficient immunity to avoid opportun...
متن کاملNew immunosuppressive regimens in lung transplantation.
Survival after lung transplantation is less than 50% after 5 yrs and is limited by infection and obliterative bronchiolitis. There is, therefore, a need for new immunosuppressive regimens if we are to attempt to improve long-term survival. Several trials in lung transplantation of new immunosuppressive agents are in the planning stages. In this article, we review the experience with a new monoc...
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Only a few randomized clinical trials have been performed so far in heart transplant recipients, mainly because of the relatively small number of heart transplants performed worldwide each year. The main focus of the few controlled trials that have been completed has been the prevention and treatment of heart allograft rejection. In the area of pharmacologic immunosuppression, both biological a...
متن کاملEffect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation
INTRODUCTION Immunosuppressants are used ubiquitously post-liver transplantation to prevent allograft rejection. However their effects on hepatocytes are unknown. Experimental data from non-liver cells indicate that immunosuppressants may promote cell death thereby driving an inflammatory response that promotes fibrosis and raises concerns that a similar effect may occur within the liver. We ev...
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ژورنال
عنوان ژورنال: Clinics
سال: 2014
ISSN: 1807-5932
DOI: 10.6061/clinics/2014(sup01)03